Interferon-γ Released by Gluten-Stimulated Celiac Disease-Specific Intestinal T Cells Enhances the Transepithelial Flux of Gluten Peptides

Celiac sprue is a T-cell-mediated enteropathy elicited in genetically susceptible individuals by dietary gluten proteins. To initiate and propagate inflammation, proteolytically resistant gluten peptides must be translocated across the small intestinal epithelium and presented to DQ2-restricted T ce...

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Bibliografske podrobnosti
Main Authors: Bethune, Michael T., Siegel, Matthew, Howles-Banerji, Samuel, Khosla, Chaitan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Pharmacology and Experimental Therapeutics 2009
Teme:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672868/
https://ncbi.nlm.nih.gov/pubmed/19218531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.148007
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