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Interferon-γ Released by Gluten-Stimulated Celiac Disease-Specific Intestinal T Cells Enhances the Transepithelial Flux of Gluten Peptides

Celiac sprue is a T-cell-mediated enteropathy elicited in genetically susceptible individuals by dietary gluten proteins. To initiate and propagate inflammation, proteolytically resistant gluten peptides must be translocated across the small intestinal epithelium and presented to DQ2-restricted T ce...

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Detalles Bibliográficos
Main Authors: Bethune, Michael T., Siegel, Matthew, Howles-Banerji, Samuel, Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Pharmacology and Experimental Therapeutics 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672868/
https://ncbi.nlm.nih.gov/pubmed/19218531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.148007
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