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Interferon-γ Released by Gluten-Stimulated Celiac Disease-Specific Intestinal T Cells Enhances the Transepithelial Flux of Gluten Peptides

Celiac sprue is a T-cell-mediated enteropathy elicited in genetically susceptible individuals by dietary gluten proteins. To initiate and propagate inflammation, proteolytically resistant gluten peptides must be translocated across the small intestinal epithelium and presented to DQ2-restricted T ce...

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מידע ביבליוגרפי
Main Authors: Bethune, Michael T., Siegel, Matthew, Howles-Banerji, Samuel, Khosla, Chaitan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Pharmacology and Experimental Therapeutics 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672868/
https://ncbi.nlm.nih.gov/pubmed/19218531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.148007
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