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Increased Superoxide and Endothelial NO Synthase Uncoupling in Blood Vessels of Bmal1-Knockout Mice

RATIONALE: Disruption of the circadian clock in mice produces vascular dysfunction as evidenced by impairments in endothelium-dependent signaling, vasomotion, and blood vessel remodeling. Although the altered function of endothelial NO synthase and the overproduction of reactive oxygen species are c...

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Hlavní autoři: Anea, Ciprian B., Cheng, Bo, Sharma, Shruti, Kumar, Sanjiv, Caldwell, R. William, Yao, Lin, Ali, M. Irfan, Merloiu, Ana M., Stepp, David W., Black, Stephen M., Fulton, David J.R., Rudic, R. Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740771/
https://ncbi.nlm.nih.gov/pubmed/22912383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.261750
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