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MMP-2 and MMP-9 dysfunction underlie vascular stiffness in circadian clock mutant mice

OBJECTIVE: The goals in the current studies were to determine if elasticity in blood vessels is compromised in circadian clock mutant mice (Bmal1-knockout/Bmal1-KO and Per-triple knockout/Per-TKO) and if matrix metalloproteinases might confer these changes in compliance. METHODS AND RESULTS: High re...

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Hlavní autoři: Anea, Ciprian B., Ali, M. Irfan, Osmond, Jessica M., Sullivan, Jennifer C., Stepp, David W., Merloiu, Ana M., Rudic, R. Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988111/
https://ncbi.nlm.nih.gov/pubmed/20829506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.214379
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