Increased Superoxide and Endothelial NO Synthase Uncoupling in Blood Vessels of Bmal1-Knockout Mice

RATIONALE: Disruption of the circadian clock in mice produces vascular dysfunction as evidenced by impairments in endothelium-dependent signaling, vasomotion, and blood vessel remodeling. Although the altered function of endothelial NO synthase and the overproduction of reactive oxygen species are c...

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Auteurs principaux: Anea, Ciprian B., Cheng, Bo, Sharma, Shruti, Kumar, Sanjiv, Caldwell, R. William, Yao, Lin, Ali, M. Irfan, Merloiu, Ana M., Stepp, David W., Black, Stephen M., Fulton, David J.R., Rudic, R. Daniel
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740771/
https://ncbi.nlm.nih.gov/pubmed/22912383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.261750
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