A construction of 4,4-spirocyclic γ-lactams by tandem radical cyclization with carbon monoxide

A straightforward synthesis of 4,4-spirocyclic indol γ-lactams by tandem radical cyclization of iodoaryl allyl azides with CO was achieved. The reaction of iodoaryl allyl azides, TTMSS and AIBN under CO pressure (80 atm) in THF at 80 °C gave the desired 4,4-spirocyclic indoline, benzofuran, and oxin...

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Библиографические подробности
Главные авторы: Ueda, Mitsuhiro, Uenoyama, Yoshitaka, Terasoma, Nozomi, Doi, Shoko, Kobayashi, Shoji, Ryu, Ilhyong, Murphy, John A
Формат: Artigo
Язык:Inglês
Опубликовано: Beilstein-Institut 2013
Предметы:
Letter
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740707/
https://ncbi.nlm.nih.gov/pubmed/23946829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.151
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