A construction of 4,4-spirocyclic γ-lactams by tandem radical cyclization with carbon monoxide

A straightforward synthesis of 4,4-spirocyclic indol γ-lactams by tandem radical cyclization of iodoaryl allyl azides with CO was achieved. The reaction of iodoaryl allyl azides, TTMSS and AIBN under CO pressure (80 atm) in THF at 80 °C gave the desired 4,4-spirocyclic indoline, benzofuran, and oxin...

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Dettagli Bibliografici
Autori principali: Ueda, Mitsuhiro, Uenoyama, Yoshitaka, Terasoma, Nozomi, Doi, Shoko, Kobayashi, Shoji, Ryu, Ilhyong, Murphy, John A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2013
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Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740707/
https://ncbi.nlm.nih.gov/pubmed/23946829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.151
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