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Targeted Antigen Delivery to DEC-205(+) Dendritic Cells for Tolerogenic Vaccination

Dendritic cells (DCs) and Foxp3-expressing CD4(+) regulatory T (Treg) cells play non-redundant roles in the maintenance of peripheral tolerance to self-antigens, thereby preventing fatal autoimmunity. A common hallmark of intra- and extra-thymic Treg cell lineage commitment is the induction of Foxp3...

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Autors principals: Petzold, Cathleen, Schallenberg, Sonja, Stern, Joel N.H., Kretschmer, Karsten
Format: Artigo
Idioma:Inglês
Publicat: SBDR - Society for Biomedical Diabetes Research 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740698/
https://ncbi.nlm.nih.gov/pubmed/23804268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.305
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