DNA vaccines encoding DEC205-targeted antigens: immunity or tolerance?

Targeting of antigens to the endocytic uptake receptor DEC205 resulted in enhanced antigen presentation by dendritic cells (DCs). In combination with adjuvants for DC maturation, proteins coupled to an antibody against DEC205 induced strong pathogen-specific immune responses, whereas without additio...

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Dettagli Bibliografici
Pubblicato in:Immunology
Autori principali: Niezold, Thomas, Storcksdieck genannt Bonsmann, Michael, Maaske, André, Temchura, Vladimir, Heinecke, Vanessa, Hannaman, Drew, Buer, Jan, Ehrhardt, Christina, Hansen, Wiebke, Überla, Klaus, Tenbusch, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515132/
https://ncbi.nlm.nih.gov/pubmed/25819746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12467
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