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DNA vaccines encoding DEC205-targeted antigens: immunity or tolerance?
Targeting of antigens to the endocytic uptake receptor DEC205 resulted in enhanced antigen presentation by dendritic cells (DCs). In combination with adjuvants for DC maturation, proteins coupled to an antibody against DEC205 induced strong pathogen-specific immune responses, whereas without additio...
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| Veröffentlicht in: | Immunology |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4515132/ https://ncbi.nlm.nih.gov/pubmed/25819746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12467 |
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