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DNA vaccines encoding DEC205-targeted antigens: immunity or tolerance?

Targeting of antigens to the endocytic uptake receptor DEC205 resulted in enhanced antigen presentation by dendritic cells (DCs). In combination with adjuvants for DC maturation, proteins coupled to an antibody against DEC205 induced strong pathogen-specific immune responses, whereas without additio...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Niezold, Thomas, Storcksdieck genannt Bonsmann, Michael, Maaske, André, Temchura, Vladimir, Heinecke, Vanessa, Hannaman, Drew, Buer, Jan, Ehrhardt, Christina, Hansen, Wiebke, Überla, Klaus, Tenbusch, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515132/
https://ncbi.nlm.nih.gov/pubmed/25819746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12467
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