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Age Increase of Estrogen Receptor-α (ERα) in Cortical Astrocytes Impairs Neurotrophic Support in Male and Female Rats
Rodent models show decreased neuronal responses to estradiol (E2) during aging (E2-desensitization) in association with reduced neuronal estrogen receptor (ER)-α, but little is known about age changes of E2-dependent astrocytic neurotrophic support. Because elevated expression of astrocyte glial fib...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Endocrine Society
2013
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740484/ https://ncbi.nlm.nih.gov/pubmed/23515288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2046 |
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