17β-Estradiol and Progesterone Regulate Expression of β-Amyloid Clearance Factors in Primary Neuron Cultures and Female Rat Brain

The accumulation of β-amyloid protein (Aβ) is a key risk factor in the development of Alzheimer's disease. The ovarian sex steroid hormones 17β-estradiol (E(2)) and progesterone (P(4)) have been shown to regulate Aβ accumulation, although the underlying mechanism(s) remain to be fully elucidate...

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Detalhes bibliográficos
Main Authors: Jayaraman, Anusha, Carroll, Jenna C., Morgan, Todd E., Lin, Sharon, Zhao, Liqin, Arimoto, Jason M., Murphy, M. Paul, Beckett, Tina L., Finch, Caleb E., Brinton, Roberta Diaz, Pike, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Neuroendocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473201/
https://ncbi.nlm.nih.gov/pubmed/22962256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1464
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