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Comparison of In Vivo Effects of Insulin on SREBP-1c Activation and INSIG-1/2 in Rat Liver and Human and Rat Adipose Tissue

The stimulatory effects of insulin on de novo lipogenesis (DNL) in the liver, where it is an important contributor to non-alcoholic fatty liver disease (NAFLD), hepatic and systemic insulin resistance, is strong and well established. In contrast, insulin plays only a minor role in DNL in adipose tis...

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Main Authors: Boden, Guenther, Salehi, Sajad, Cheung, Peter, Homko, Carol, Song, Weiwei, Loveland-Jones, Catherine, Jayarajan, Senthil
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740458/
https://ncbi.nlm.nih.gov/pubmed/23913732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20134
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