Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue

Endoplasmic reticulum (ER) stress is increased in obesity and is postulated to be a major contributor to many obesity-related pathologies. Little is known about what causes ER stress in obese people. Here, we show that insulin upregulated the unfolded protein response (UPR), an adaptive reaction to...

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Detalhes bibliográficos
Main Authors: Boden, Guenther, Cheung, Peter, Salehi, Sajad, Homko, Carol, Loveland-Jones, Catherine, Jayarajan, Senthil, Stein, T. Peter, Williams, Kevin Jon, Liu, Ming-Lin, Barrero, Carlos A., Merali, Salim
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931405/
https://ncbi.nlm.nih.gov/pubmed/24130338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0906
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