Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue

Endoplasmic reticulum (ER) stress is increased in obesity and is postulated to be a major contributor to many obesity-related pathologies. Little is known about what causes ER stress in obese people. Here, we show that insulin upregulated the unfolded protein response (UPR), an adaptive reaction to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Boden, Guenther, Cheung, Peter, Salehi, Sajad, Homko, Carol, Loveland-Jones, Catherine, Jayarajan, Senthil, Stein, T. Peter, Williams, Kevin Jon, Liu, Ming-Lin, Barrero, Carlos A., Merali, Salim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2014
Pynciau:
Metabolism
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931405/
https://ncbi.nlm.nih.gov/pubmed/24130338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0906
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