A Novel Function for the Conserved Glutamate Residue in the Walker B Motif of Replication Factor C

In all domains of life, sliding clamps tether DNA polymerases to DNA to increase the processivity of synthesis. Clamp loaders load clamps onto DNA in a multi-step process that requires ATP binding and hydrolysis. Like other AAA+ proteins, clamp loaders contain conserved Walker A and Walker B sequenc...

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Bibliographic Details
Main Authors: Chiraniya, Ankita, Finkelstein, Jeff, O’Donnell, Mike, Bloom, Linda B.
Format: Artigo
Language:Inglês
Published: MDPI 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740443/
https://ncbi.nlm.nih.gov/pubmed/23946885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes4020134
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