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Role of the conserved lysine within the Walker A motif of human DMC1

During meiosis, the RAD51 recombinase and its meiosis-specific homolog DMC1 mediate DNA strand exchange between homologous chromosomes. The proteins form a right-handed nucleoprotein complex on ssDNA called the presynaptic filament. In an ATP-dependent manner, the presynaptic filament searches for h...

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Autori principali: Sharma, Deepti, Say, Amanda F., Ledford, LeAnna L., Hughes, Ami J., Sehorn, Hilarie A., Dwyer, Donard S., Sehorn, Michael G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677694/
https://ncbi.nlm.nih.gov/pubmed/23182424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.005
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