The Adipokine Leptin Increases Skeletal Muscle Mass and Significantly Alters Skeletal Muscle miRNA Expression Profile in Aged Mice

Age-associated loss of muscle mass, or sarcopenia, contributes directly to frailty and an increased risk of falls and fractures among the elderly. Aged mice and elderly adults both show decreased muscle mass as well as relatively low levels of the fat-derived hormone leptin. Here we demonstrate that...

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Main Authors: Hamrick, Mark W., Herberg, Samuel, Arounleut, Phonepasong, He, Hong-Zhi, Shiver, Austin, Qi, Rui-Qun, Zhou, Li, Isales, Carlos M., Mi, Qing-Sheng
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740337/
https://ncbi.nlm.nih.gov/pubmed/20800581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.08.079
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