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The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells
The Pak4 protein kinase, normally expressed at low level in the mammary gland, is commonly overexpressed in breast cancer. Overexpression of Pak4 transforms mouse mammary epithelial cells in vitro and renders these cells tumorigenic in athymic mice in vivo. Here we show that Pak4 is also required fo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740299/ https://ncbi.nlm.nih.gov/pubmed/23732710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.13 |
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