Defining MAP3Kinases Required for MDA-MB-231 Cell Tumor Growth and Metastasis

Analysis of patient tumors suggests multiple MAP3kinases (MAP3Ks) are critical for growth and metastasis of cancer cells. MAP3Ks selectively control the activation of ERK1/2, JNK, p38 and ERK5 in response to receptor tyrosine kinases and GTPases. We used MDA-MB-231 cells because of their ability to...

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Detalhes bibliográficos
Main Authors: Cronan, Mark R., Nakamura, Kazuhiro, Johnson, Nancy L., Granger, Deborah A., Cuevas, Bruce D., Wang, Jian-Guo, Mackman, Nigel, Scott, John E., Dohlman, Henrik G., Johnson, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297722/
https://ncbi.nlm.nih.gov/pubmed/22139075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.544
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