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Functional differences between Streptococcus pyogenes cluster 1 and cluster 2b streptokinases are determined by their β-domains

Cluster 1 streptokinases (SK1) from Streptococcus pyogenes (GAS) show substantially higher human plasminogen (hPg) activation activities and tighter hPg binding affinities than cluster 2b streptokinases (SK2b) in solution. The extent to which the different domains of SK are responsible for these dif...

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מידע ביבליוגרפי
Main Authors: Zhang, Yueling, Liang, Zhong, Glinton, Kristofor, Ploplis, Victoria A., Castellino, Francis J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740169/
https://ncbi.nlm.nih.gov/pubmed/23474243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.02.033
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