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Functional differences between Streptococcus pyogenes cluster 1 and cluster 2b streptokinases are determined by their β-domains
Cluster 1 streptokinases (SK1) from Streptococcus pyogenes (GAS) show substantially higher human plasminogen (hPg) activation activities and tighter hPg binding affinities than cluster 2b streptokinases (SK2b) in solution. The extent to which the different domains of SK are responsible for these dif...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740169/ https://ncbi.nlm.nih.gov/pubmed/23474243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.02.033 |
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