Optimal dose of busulfan for depleting testicular germ cells of recipient mice before spermatogonial transplantation

Successful spermatogonial transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan (Myleran), is commonly used for preparing a recipient mouse before transplantation, the optimal dose of th...

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Bibliographic Details
Main Authors: Wang, De-Zhi, Zhou, Xin-Hua, Yuan, Yu-Lin, Zheng, Xin-Min
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739084/
https://ncbi.nlm.nih.gov/pubmed/20010847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2009.67
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