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Optimal dose of busulfan for depleting testicular germ cells of recipient mice before spermatogonial transplantation

Successful spermatogonial transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan (Myleran), is commonly used for preparing a recipient mouse before transplantation, the optimal dose of th...

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Autors principals: Wang, De-Zhi, Zhou, Xin-Hua, Yuan, Yu-Lin, Zheng, Xin-Min
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739084/
https://ncbi.nlm.nih.gov/pubmed/20010847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2009.67
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