Testicular Busulfan Injection in Mice to Prepare Recipients for Spermatogonial Stem Cell Transplantation Is Safe and Non-Toxic

Current methods of administering busulfan to remove the endogenous germ cells cause hematopoietic toxicity, require special instruments and a narrow transplantation time. We use a direct testicular injection of busulfan method for preparing recipients for SSC transplantation. Male ICR mice (recipien...

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Publicat a:PLoS One
Autors principals: Qin, YuSheng, Liu, Ling, He, YaNan, Wang, Chen, Liang, MingYuan, Chen, XiaoLi, Hao, HaiSheng, Qin, Tong, Zhao, XueMing, Wang, Dong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752460/
https://ncbi.nlm.nih.gov/pubmed/26871566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148388
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