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Optimal dose of busulfan for depleting testicular germ cells of recipient mice before spermatogonial transplantation

Successful spermatogonial transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan (Myleran), is commonly used for preparing a recipient mouse before transplantation, the optimal dose of th...

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Detalhes bibliográficos
Main Authors: Wang, De-Zhi, Zhou, Xin-Hua, Yuan, Yu-Lin, Zheng, Xin-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739084/
https://ncbi.nlm.nih.gov/pubmed/20010847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2009.67
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