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Association of telomere shortening in myocardium with heart weight gain and cause of death

We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly telomere reduction rate of 20 base pairs in the myocardium. There was a significant correlation between myocardial telomere and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Terai, Masanori, Izumiyama-Shimomura, Naotaka, Aida, Junko, Ishikawa, Naoshi, Sawabe, Motoji, Arai, Tomio, Fujiwara, Mutsunori, Ishii, Akio, Nakamura, Ken-ichi, Takubo, Kaiyo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738945/
https://ncbi.nlm.nih.gov/pubmed/23929129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02401
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