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Association of telomere shortening in myocardium with heart weight gain and cause of death

We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly telomere reduction rate of 20 base pairs in the myocardium. There was a significant correlation between myocardial telomere and...

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Bibliografische gegevens
Hoofdauteurs: Terai, Masanori, Izumiyama-Shimomura, Naotaka, Aida, Junko, Ishikawa, Naoshi, Sawabe, Motoji, Arai, Tomio, Fujiwara, Mutsunori, Ishii, Akio, Nakamura, Ken-ichi, Takubo, Kaiyo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738945/
https://ncbi.nlm.nih.gov/pubmed/23929129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02401
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