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Association of telomere shortening in myocardium with heart weight gain and cause of death

We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly telomere reduction rate of 20 base pairs in the myocardium. There was a significant correlation between myocardial telomere and...

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Detalhes bibliográficos
Main Authors: Terai, Masanori, Izumiyama-Shimomura, Naotaka, Aida, Junko, Ishikawa, Naoshi, Sawabe, Motoji, Arai, Tomio, Fujiwara, Mutsunori, Ishii, Akio, Nakamura, Ken-ichi, Takubo, Kaiyo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738945/
https://ncbi.nlm.nih.gov/pubmed/23929129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02401
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