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Insight into Helicase Mechanism and Function Revealed through Single-Molecule Approaches

Helicases are a class of nucleic acid motors that catalyze NTP-dependent unwinding of nucleic acid duplexes into single-strands, a reaction essential to all areas of nucleic acid metabolism. In the last decade, single-molecule technology has proven to be highly useful in revealing mechanistic insigh...

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Autori principali: Yodh, Jaya G., Schlierf, Michael, Ha, Taekjip
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738580/
https://ncbi.nlm.nih.gov/pubmed/20682090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583510000107
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