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Structural Dynamics of Human Telomeric G-Quadruplex Loops Studied by Molecular Dynamics Simulations

Loops which are linkers connecting G-strands and supporting the G-tetrad core in G-quadruplex are important for biological roles of G-quadruplexes. TTA loop is a common sequence which mainly resides in human telomeric DNA (hTel) G-quadruplex. A series of molecular dynamics (MD) simulations were carr...

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書目詳細資料
Main Authors: Zhu, Hong, Xiao, Shiyan, Liang, Haojun
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738534/
https://ncbi.nlm.nih.gov/pubmed/23951152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071380
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