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Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts
Heart rate reduction (HRR) is an important target in the management of patients with chronic stable angina. Most available drugs for HRR, such as β-blockers, have adverse effects, including on cardiac energy substrate metabolism, a well-recognized determinant of cardiac homeostasis. This study aimed...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738505/ https://ncbi.nlm.nih.gov/pubmed/21257916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01034.2010 |
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