Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice

BACKGROUND AND PURPOSE: High resting heart rate is a predictor for total and cardiovascular mortality independent of other risk factors in patients with coronary artery disease. We tested the hypothesis that a reduction of resting heart rate with the cardiac pacemaker I(f) current inhibitor ivabradi...

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Bibliografiske detaljer
Main Authors: Drouin, A, Gendron, M-È, Thorin, E, Gillis, M-A, Mahlberg-Gaudin, F, Tardif, J-C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2439858/
https://ncbi.nlm.nih.gov/pubmed/18414390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.116
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