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Gene Expression Regulation by Upstream Open Reading Frames and Human Disease
Upstream open reading frames (uORFs) are major gene expression regulatory elements. In many eukaryotic mRNAs, one or more uORFs precede the initiation codon of the main coding region. Indeed, several studies have revealed that almost half of human transcripts present uORFs. Very interesting examples...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738444/ https://ncbi.nlm.nih.gov/pubmed/23950723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003529 |
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