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Investigation of Homeodomain Membrane Translocation Properties: Insights from the Structure Determination of Engrailed-2 Homeodomain in Aqueous and Membrane-Mimetic Environments

In addition to their well-known DNA-binding properties, homeodomains have the ability to efficiently translocate across biological membranes through still poorly-characterized mechanisms. To date, most biophysical studies addressing the mechanisms of internalization have focused on small synthetic p...

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Dettagli Bibliografici
Autori principali: Carlier, Ludovic, Balayssac, Stéphane, Cantrelle, François-Xavier, Khemtémourian, Lucie, Chassaing, Gérard, Joliot, Alain, Lequin, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738247/
https://ncbi.nlm.nih.gov/pubmed/23931315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.024
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