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Myostatin (GDF-8) Inhibits Chondrogenesis and Chondrocyte Proliferation In Vitro by Suppressing Sox-9 Expression

Here, we investigate a possible direct role for myostatin in chondrogenesis. First, we examined the effects of myostatin on the proliferation of bone marrow stromal cells (BMSCs) and epiphyseal growth plate (EGP) chondrocytes isolated from myostatin-deficient mice. Results show that myostatin defici...

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Main Authors: Elkasrawy, Moataz, Fulzele, Sadanand, Bowser, Matthew, Wenger, Karl, Hamrick, Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738019/
https://ncbi.nlm.nih.gov/pubmed/21756198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2011.599324
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