Myostatin (GDF-8) Inhibits Chondrogenesis and Chondrocyte Proliferation In Vitro by Suppressing Sox-9 Expression

Here, we investigate a possible direct role for myostatin in chondrogenesis. First, we examined the effects of myostatin on the proliferation of bone marrow stromal cells (BMSCs) and epiphyseal growth plate (EGP) chondrocytes isolated from myostatin-deficient mice. Results show that myostatin defici...

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Bibliographic Details
Main Authors: Elkasrawy, Moataz, Fulzele, Sadanand, Bowser, Matthew, Wenger, Karl, Hamrick, Mark
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738019/
https://ncbi.nlm.nih.gov/pubmed/21756198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2011.599324
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