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Myostatin (GDF-8) Deficiency Increases Fracture Callus Size, Sox-5 Expression, and Callus Bone Volume

Myostatin (GDF-8) is a negative regulator of skeletal muscle growth and mice lacking myostatin show increased muscle mass. We have previously shown that myostatin deficiency increases bone strength and biomineralization throughout the skeleton, and others have demonstrated that myostatin is expresse...

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Detalhes bibliográficos
Main Authors: Kellum, Ethan, Starr, Harlan, Arounleut, Phonepasong, Immel, David, Fulzele, Sadanand, Wenger, Karl, Hamrick, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648293/
https://ncbi.nlm.nih.gov/pubmed/18852073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.08.126
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