In vivo imaging of endogenous pancreatic beta cell mass in healthy and type 1 diabetic subjects using [(18)F]FP-(+)-DTBZ and PET

The ability to non-invasively measure endogenous pancreatic β-cell mass (BCM) would accelerate research on the pathophysiology of diabetes and revolutionize the preclinical development of new treatments, the clinical assessment of therapeutic efficacy, and the early diagnosis and subsequent monitori...

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Main Authors: Normandin, Marc D., Petersen, Kitt F., Ding, Yu-Shin, Lin, Shu-Fei, Naik, Sarita, Fowles, Krista, Skovronsky, Daniel M., Herold, Kevan C., McCarthy, Timothy J., Calle, Roberto A., Carson, Richard E., Treadway, Judith L., Cline, Gary W.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737743/
https://ncbi.nlm.nih.gov/pubmed/22573821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.100545
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