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Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico

Cellular systems are generally robust against fluctuations of intracellular parameters such as gene expression level. However, little is known about expression limits of genes required to halt cellular systems. In this study, using the fission yeast Schizosaccharomyces pombe, we developed a genetic...

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Autors principals: Moriya, Hisao, Chino, Ayako, Kapuy, Orsolya, Csikász-Nagy, Attila, Novák, Béla
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737731/
https://ncbi.nlm.nih.gov/pubmed/22146300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.91
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