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Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico

Cellular systems are generally robust against fluctuations of intracellular parameters such as gene expression level. However, little is known about expression limits of genes required to halt cellular systems. In this study, using the fission yeast Schizosaccharomyces pombe, we developed a genetic...

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Main Authors: Moriya, Hisao, Chino, Ayako, Kapuy, Orsolya, Csikász-Nagy, Attila, Novák, Béla
格式: Artigo
語言:Inglês
出版: European Molecular Biology Organization 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737731/
https://ncbi.nlm.nih.gov/pubmed/22146300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.91
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