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Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico

Cellular systems are generally robust against fluctuations of intracellular parameters such as gene expression level. However, little is known about expression limits of genes required to halt cellular systems. In this study, using the fission yeast Schizosaccharomyces pombe, we developed a genetic...

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Hlavní autoři: Moriya, Hisao, Chino, Ayako, Kapuy, Orsolya, Csikász-Nagy, Attila, Novák, Béla
Médium: Artigo
Jazyk:Inglês
Vydáno: European Molecular Biology Organization 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737731/
https://ncbi.nlm.nih.gov/pubmed/22146300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.91
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