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Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex

Recruitment of cofactors to specific DNA sites is integral for specificity in gene regulation. As a model system, we examined how targeting and transcriptional control of the sulfur metabolism genes in Saccharomyces cerevisiae is governed by recruitment of the transcriptional co-activator Met4. We d...

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Detalhes bibliográficos
Main Authors: Siggers, Trevor, Duyzend, Michael H, Reddy, Jessica, Khan, Sidra, Bulyk, Martha L
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737730/
https://ncbi.nlm.nih.gov/pubmed/22146299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.89
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