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Density-dependent cooperative non-specific binding in solid-phase SELEX affinity selection

The non-specific binding of undesired ligands to a target is the primary factor limiting the enrichment of tight-binding ligands in affinity selection. Solution-phase non-specific affinity is determined by the free-energy of ligand binding to a single target. However, the solid-phase affinity might...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ozer, Abdullah, White, Brian S., Lis, John T., Shalloway, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737557/
https://ncbi.nlm.nih.gov/pubmed/23737446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt477
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