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UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins

It is thought that the SelenoCysteine Insertion Sequence (SECIS) element and UGA codon are sufficient for selenocysteine (Sec) insertion. However, we found that UGA supported Sec insertion only at its natural position or in its close proximity in mammalian thioredoxin reductase 1 (TR1). In contrast,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Turanov, Anton A., Lobanov, Alexei V., Hatfield, Dolph L., Gladyshev, Vadim N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737529/
https://ncbi.nlm.nih.gov/pubmed/23716634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt409
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