KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family

Histone methylation is implicated in various biological and pathological processes including cancer development. In this study, we discovered that ectopic expression of KDM5B, a histone H3 lysine 4 (H3K4) demethylase, promoted epithelial-mesenchymal transition (EMT) of cancer cells. KDM5B increased...

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Bibliographische Detailangaben
Hauptverfasser: Enkhbaatar, Zanabazar, Terashima, Minoru, Oktyabri, Dulamsuren, Tange, Shoichiro, Ishimura, Akihiko, Yano, Seiji, Suzuki, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737312/
https://ncbi.nlm.nih.gov/pubmed/23759590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25142
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