MEG3 Long Noncoding RNA Contributes to the Epigenetic Regulation of Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines

Histone methylation is implicated in a number of biological and pathological processes, including cancer development. In this study, we investigated the molecular mechanism for the recruitment of Polycomb repressive complex-2 (PRC2) and its accessory component, JARID2, to chromatin, which regulates...

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Vydáno v:J Biol Chem
Hlavní autoři: Terashima, Minoru, Tange, Shoichiro, Ishimura, Akihiko, Suzuki, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217702/
https://ncbi.nlm.nih.gov/pubmed/27852821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750950
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