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KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial–mesenchymal transition in lung and pancreatic cancer cell lines

Polycomb repressive complex-1 (PRC1) induces transcriptional repression by regulating monoubiquitination of lysine 119 of histone H2A (H2AK119) and as such is involved in a number of biological and pathological processes including cancer development. Previously we demonstrated that PRC2, which catal...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Wanna-Udom, Sasithorn, Terashima, Minoru, Suphakhong, Kusuma, Ishimura, Akihiko, Takino, Takahisa, Suzuki, Takeshi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948487/
https://ncbi.nlm.nih.gov/pubmed/33779563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015502
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