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Inter-telomeric recombination is present in telomerase-positive human cells

Immortal cells require a mechanism of telomere length control in order to divide infinitely. One mechanism is telomerase, an enzyme that compensates the loss of telomeric DNA. The second mechanism is the alternative lengthening of telomeres (ALT) pathway. In ALT pathway cells, homologous recombinati...

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Detalhes bibliográficos
Main Authors: Dlaska, Margit, Schöffski, Patrick, Bechter, Oliver E.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737311/
https://ncbi.nlm.nih.gov/pubmed/23759591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25136
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