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Inter-telomeric recombination is present in telomerase-positive human cells
Immortal cells require a mechanism of telomere length control in order to divide infinitely. One mechanism is telomerase, an enzyme that compensates the loss of telomeric DNA. The second mechanism is the alternative lengthening of telomeres (ALT) pathway. In ALT pathway cells, homologous recombinati...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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Landes Bioscience
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737311/ https://ncbi.nlm.nih.gov/pubmed/23759591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25136 |
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