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Inter-telomeric recombination is present in telomerase-positive human cells

Immortal cells require a mechanism of telomere length control in order to divide infinitely. One mechanism is telomerase, an enzyme that compensates the loss of telomeric DNA. The second mechanism is the alternative lengthening of telomeres (ALT) pathway. In ALT pathway cells, homologous recombinati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dlaska, Margit, Schöffski, Patrick, Bechter, Oliver E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737311/
https://ncbi.nlm.nih.gov/pubmed/23759591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25136
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