PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individuals with European ancestry. Since the rs2476601 risk...

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Detalhes bibliográficos
Main Authors: Namjou, Bahram, Kim-Howard, Xana, Sun, Celi, Adler, Adam, Chung, Sharon A., Kaufman, Kenneth M., Kelly, Jennifer A., Glenn, Stuart B., Guthridge, Joel M., Scofield, Robert H., Kimberly, Robert P., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Kim, Jae-Hoon, Choi, Jiyoung, Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Boackle, Susan A., Freedman, Barry I., Tsao, Betty P., Langefeld, Carl D., Vyse, Timothy J., Jacob, Chaim O., Pons-Estel, Bernardo, Niewold, Timothy B., Moser Sivils, Kathy L., Merrill, Joan T., Anaya, Juan-Manuel, Gilkeson, Gary S., Gaffney, Patrick M., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Harley, John B., Criswell, Lindsey A., James, Judith A., Nath, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737240/
https://ncbi.nlm.nih.gov/pubmed/23950893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069404
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