PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individuals with European ancestry. Since the rs2476601 risk...

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Main Authors: Namjou, Bahram, Kim-Howard, Xana, Sun, Celi, Adler, Adam, Chung, Sharon A., Kaufman, Kenneth M., Kelly, Jennifer A., Glenn, Stuart B., Guthridge, Joel M., Scofield, Robert H., Kimberly, Robert P., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Kim, Jae-Hoon, Choi, Jiyoung, Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Boackle, Susan A., Freedman, Barry I., Tsao, Betty P., Langefeld, Carl D., Vyse, Timothy J., Jacob, Chaim O., Pons-Estel, Bernardo, Niewold, Timothy B., Moser Sivils, Kathy L., Merrill, Joan T., Anaya, Juan-Manuel, Gilkeson, Gary S., Gaffney, Patrick M., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Harley, John B., Criswell, Lindsey A., James, Judith A., Nath, Swapan K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737240/
https://ncbi.nlm.nih.gov/pubmed/23950893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069404
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