The Fas/Fas Ligand Death Receptor Pathway Contributes to Phenylalanine-Induced Apoptosis in Cortical Neurons

Phenylketonuria (PKU), an autosomal recessive disorder of amino acid metabolism caused by mutations in the phenylalanine hydroxylase (PAH) gene, leads to childhood mental retardation by exposing neurons to cytotoxic levels of phenylalanine (Phe). A recent study showed that the mitochondria-mediated...

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Detaylı Bibliyografya
Asıl Yazarlar: Huang, Xiaodong, Lu, Zhaohui, Lv, Zhongwei, Yu, Tingting, Yang, Peirong, Shen, Yongnian, Ding, Yu, Fu, Da, Zhang, Xiaoping, Fu, Qihua, Yu, Yongguo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737091/
https://ncbi.nlm.nih.gov/pubmed/23940767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071553
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