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In-vitro/In-vivo comparison of leuprolide acetate release from an in-situ forming plga system

A poly (lactide-co-glycolide) (PLGA) implant was used to control the release profile of leuprolide acetate (LA) drug. The system is an in-situ polymeric precipitation system. And the formulation consisted of PLGA polymer, LA drug and N-methyl-2-pyrrolidon solvent with no additives. First, the formul...

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Detalhes bibliográficos
Main Authors: Mashayekhi, Roya, Mobedi, Hamid, Najafi, Jamal, Enayati, Marjan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737027/
https://ncbi.nlm.nih.gov/pubmed/23856431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-21-57
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