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Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann–Pick disease, type C1
Niemann–Pick disease, type C1 (NPC1), which arises from a mutation in the NPC1 gene, is characterized by abnormal cellular storage and transport of cholesterol and other lipids that leads to hepatic disease and progressive neurological impairment. Oxidative stress has been hypothesized to contribute...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736870/ https://ncbi.nlm.nih.gov/pubmed/23666527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt206 |
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